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  • tetris11
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    2 hours ago

    where does the tolerance come from though? With alcohol it’s very clear that there’s one organ doing the heavy lifting. With weed, I have no idea.

    To each their own though, not trying to pressure anybody.

    Of course! Likewise, I’m not trying to shame anyone for picking weed over beer. Each to their own

    Edit: Apparently it’s “CB1 receptor density” in your brain that handles the tolerance.

    • WeirdGoesPro@lemmy.dbzer0.com
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      6 minutes ago

      Indeed, a lot of drugs that are non toxic have tolerance created in the brain, while more toxic drugs have to get processed by the kidneys and liver, which is why the functioning of those organs contributes to tolerance.