Linux mint is a really easy and simple starting point. Fedora and openSUSE tumbleweed are a tad more advanced but allow more selection on your desktop environment (mint uses cinnamon, while Fedora and SUSE have both KDE and Gnome options) and thus can potentially support things like variable refresh rate and, when it gets support from KDE later this year, HDR.

For peripherals, if it’s razor or Logitech, it’ll just work and have community apps made to configure them. I personally like Keychron’s stuff so that’s what I use and that’s fully Linux compatible, it does require some setup to work though. HDR is unsupported for the time being, but variable refresh (gsync/freesync) is in the KDE Plasma desktop environment under Wayland. On the topic of Wayland, if you want to make use of this new display protocol you’ll need an AMD graphics card, as NVIDIA has been slacking with their Linux drivers. NVIDIA is getting better but it’s not stable enough on Wayland for the laymen. In the case of only having an NVIDIA, X11 works fine, but it’s just missing some features.

Also you won’t need JavaScript, 90% of what you do will be through the GUI (depending on the distro), especially once you’re set up. I know Fedora needs to enable rpmFusion, NVIDIA repos if on NVIDIA, and install codecs for hardware accelerated playback. Mint doesn’t have these issues for the most part, though you’ll want to enable flatpak’s and consider disabling snaps. Mint already includes a graphical installer for NVIDIA and includes the codecs needed for hardware accelerated playback