• Stoned_Ape
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    2 years ago

    Do you have a resource on the testing they did?

    It was a German meta study of I believe 12 studies where placebo was tested against both synthetic ADs and St. Johns Wort (which is what I take). That was 13 years ago. I try to see what I can find.

      • Stoned_Ape
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        2 years ago

        I think it was this one: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD000448.pub3/full

        You can find the full text here (Click on the blue buttons [Libgen] to download): https://libgen.li/edition.php?id=36416454

        Very interesting bit: “Both in placebo‐controlled trials and in comparisons with standard antidepressants, trials from German‐speaking countries reported findings more favourable to hypericum.”

        That’s odd. I wonder what the reason might be.

        Trying to ping the user @lemmyreader@lemmy.ml Please tell me if that worked. :)

        • lemmyreader
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          2 years ago

          Thanks for sharing the web links.

          Trying to ping the user @lemmyreader@lemmy.ml Please tell me if that worked. :)

          Worked :) And let’s ping in the original question poster as well @Amicchan@lemmy.ml just in case.

          Hypericum (St. John’s Wort) pills can be bought in some regular shops here in Europe. I have a tendency to use them in the Winter, but this time it didn’t go so well. I also have it as tea, maybe I’ll give that a try again when needed. Luckily I found other ways to feel better. Odd thing about the results for German speaking countries.

          Trials from German-speaking countries reported more positive findings than trials from other countries (RR = 1.78; 95%CI 1.42 to 2.25 vs.1.07; 95% CI 0.88 to 1.31, respectively; see comparison 1.5 and Figure 2).

          What do these numbers mean exactly ? Was it a huge difference or not so much ?

    • lemmyreader
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      2 years ago

      Interesting that you mention St.Johns Wort, it is something which I used from time to time, and I like that it is natural with minimal side effects. (I’ve been told that women should be very careful with this as it conflict with some contraceptives).

      • Stoned_Ape
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        2 years ago

        St. Johns Wort generally changes the outcome of dosage of medications. A lot of stuff should be taken in different doses. Pill contraceptives are reduced in efficacy by St. Johns Wort, and that can mean that the protection is lowered.