I haven’t used Tiktok ever, but I hear it’s a good destination for fun content. Is there a way to access Tiktok on the desktop, possibly an alternative frontend from the official one? Similar to libreddit for reddit, Bibliogram for Instagram, Whoogle for Google.

+1 to this. Tailscale makes it incredibly easy to create that mesh VPN. Get your pihole listening on the Tailscale network and that takes care of the ad-blocking part. About changing the IP address though, that’s a different topic. Will need to have a commercial VPN configured on that server and use that as an exit node.