Fasting for a week:

  • Causes significant changes in protein levels across various organs.
  • May have health benefits beyond weight loss, but only after 3 days.
  • Switches energy source from glucose to fat after 2-3 days.
  • Average weight loss of 5.7 kg (fat and muscle), with most fat loss sustained after 3 days of eating.

Implications:

  • Provides insights into the molecular basis of fasting’s health effects.
  • Paves the way for developing alternative treatments based on fasting benefits.
  • Confirms historical use of fasting for specific health conditions.
    • MotoAsh@lemmy.world
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      8 months ago

      I mean, not eating is a diet? This seems to be directly addressing one part of that equation: you don’t even ‘need’ exercise for simple fat loss. Though of course an actual balance you can keep up perpetually is much better, but this definitely directly touches diet.

    • Kusimulkku@lemm.ee
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      8 months ago

      I’ve heard on quite a few shows that exercising doesn’t actually do much for losing weight. It’s healthy for you but not a good way to lose weight, apparently. Pretty interesting.

      • SendMePhotos@lemmy.world
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        8 months ago

        I lost 60lbs by sitting on my ass playing video games, counting calories (1500-1800 + one cheat day per week).

      • NineMileTower@lemmy.world
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        8 months ago

        Agreed. You can’t outrun the fork, however good habits stack on each other and there’s a lot to be said about mental health benefits. They tend to go hand in hand.

    • Fedizen@lemmy.world
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      8 months ago

      I can’t imagine human diets used to be as predictable as they are now, especially in winter. Attempting a diet that includes fasting doesnt seem unreasonable as part of a larger plan.

    • constantokra@lemmy.one
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      8 months ago

      Doctors will recommend fasting, or at least intermittent fasting, for a variety of conditions. Particulaly it helps you deal with insulin resistance, which isn’t just diabetes. It could be why you’re carrying a lot of weight, and it could also have to do with anxiety.

      ‘Diet’ and exercise don’t always work for everyone, or for all problems, and insisting that it does really damages the people who have legitimately put a lot of effort into both those things without seeing meaningful results. Not only do they not see benefits from their hard work, they also start to feel like they’re just not doing enough even if they are.

      You should really look into some of the actual science behind fasting, and also behind caloric reduction and exercise before you criticize it so dismissively.

        • Omgpwnies@lemmy.world
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          8 months ago

          Yeah, we’re aware that the laws of thermodynamics must be followed. The study clearly showed that if you set CI to zero, and CO remains nonzero, you lose weight.

        • boonhet@lemm.ee
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          8 months ago

          CICO is science, but your CO can change based on your CI and there are cases where it’s very hard to keep CI down. For an example, I have ADHD, it’s legitimately extremely difficult to keep track of what I eat, eating one meal a day was about the only thing that helped. I believe I was also prediabetic (based on my glucose levels before my weight loss) and eating a small meal, particularly if rich in carbs, made me go hangrryyyyyyy later, but in a fasted state I was completely OK. Now I’ve lost something around the neighbourhood of 30 kilos/65 lbs and don’t need to do one meal a day anymore, because I feel sated from much less food AND stay sated way longer.

          This is why different people need their different tricks for weight loss. Find out how to reduce your hunger first and foremost, then focus on actually reducing calories. If fasting leads to being able to handle caloric restriction, it’s awesome. If not, try something else. But don’t restrict calories in a way that makes you continuously feel hungry, because that just won’t work long term.