Sensory hypersensitivity in mice with Grin2b mutations is associated with hyperactivity in the anterior cingulate cortex and increased connectivity throughout the brain. A research team led by Director Kim Eunjoon of the Center for Synaptic Brain Dysfunctions and Director Kim Seong-Gi of the Center

This study has identified the anterior cingulate cortex (ACC) as a key area in the brain responsible for sensory hypersensitivity in autism spectrum disorders. Utilizing a mouse model with a Grin2b gene mutation, heightened neural activity and connectivity in the ACC was observed. Suppressing this hyperactivity normalized the sensory hypersensitivity, offering new insights into treatment options

https://www.nature.com/articles/s41380-024-02572-y (open access)

  • FoxyFerengi@lemm.ee
    6·
    6 months ago

    I guess my confusion with that lies with an additional diagnosis I have: AvPD. Treatment for the pd has been hugely beneficial for me, where I don’t think treating social issues in autism can/should be beneficial or necessary. I’m not disagreeing with your take, I think similar brain structures can have similar symptoms. I just would hate to put anyone with autism through the therapy I have solely because it helped me navigate the world better.

    If I had been diagnosed with autism, I would never gone through this treatment. I guess, as my therapist puts it “we don’t want to change autism” where the world does want to change personality disorders