• sqgl@beehaw.org
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    7 months ago

    What does it mean for drug B to be X times stronger than drug A? Is it per milligram? Per LD50?

    • pedroapero
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      7 months ago

      That would be the required dosage to get a regular hit (or to feel something maybe)

        • tryptaminev 🇵🇸 🇺🇦 🇪🇺@feddit.de
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          7 months ago

          https://en.wikipedia.org/wiki/List_of_benzimidazole_opioids

          There is the Analgetic Potency listed, which would be the weight factor. However looking at the individual compounds the numbers can vary drastically, i didnt find any LD50 information and many of them being just completely new.

          For reference Heroin has a potency of about 2 compared to Morphine and Fentanyl has a potency of about 100.

          So this is uncharted territory both in terms of potency and the compounds themselves. There exists no knowledge about the precise effects, about side effects, long term harm, addiction…