Mine is the Bloom from Torment: Tides of Numenera. I love the fleshy bits. I love the everyday gruesome horror becoming an everyday thing for the people who live there. I love the literally organic surroundings. It’s just by far my favorite location in any game ever. :)
The All-Star Rest Area in Super Smash Bros Brawl. Extremely calming and oddly serene. Giving the player time to catch a breath between the breakneck All-Star fights. Stay as long as you want, and the music was very nice.