I have not kept up on antibiotic resistance research, or phages in recent years.
I do recall a number of years ago, I believe in the US, someone scooping up pond and garden soil samples looking for new phages.
A quick search though, does show work on “phagemids”; the following article does mention that phages can cause harm to the human host by releasing harmful toxins in the bacteria when cell lysis is performed (potentially causing sepsis, or death), as well as bacteria do also develop resistance to phages over time.
I have not kept up on antibiotic resistance research, or phages in recent years.
I do recall a number of years ago, I believe in the US, someone scooping up pond and garden soil samples looking for new phages.
A quick search though, does show work on “phagemids”; the following article does mention that phages can cause harm to the human host by releasing harmful toxins in the bacteria when cell lysis is performed (potentially causing sepsis, or death), as well as bacteria do also develop resistance to phages over time.
https://news.mit.edu/2015/engineered-particles-kill-harmful-bacteria-0625
Don’t antibiotics also cause cell lysis? especially those like beta-lactams that interfere with cell wall maintenance