Microsoft is bringing popular programming language Python to Excel. A public preview of the feature is available today, allowing Excel users to manipulate and analyze data from Python.
You won’t need to install any additional software or set up an add-on to access the functionality, as Python integration in Excel will be part of Excel’s built-in connectors and Power Query. Microsoft is also adding a new PY function that allows Python data to be exposed within the grid of an Excel spreadsheet. Through a partnership with Anaconda, an enterprise Python repository, popular Python libraries like pandas, statsmodels, and Matplotlib will be available in Excel.
I would never use Python outside of Excel just like I never use visual basic outside of Excel.
I would use it for the same reason I (rarely) use vba in Excel, some things you can’t do with formulas.