Disclaimer! Work In Progress! See source code. I recently read this wonderful blog post about using 17th Century Dutch fonts on the web. And, because I'm an idiot, I decided to try and build something similar using Shakespeare's first folio as a template. Now, before setting off on a journey, it is worth seeing if [...]
Of course they do, better than ever actually. Google OpenType ligatures, for example. You can even use those on the web using CSS.
Some fonts have hundreds of different ligatures.