I’ve got one coming up soon and am nervous as hell, as usual.

  • uptoke@kbin.social
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    1 year ago

    Curious about the cocaine comment. Does it interact with the drug that will make you sick or just a bad time mentally?

      • blaine@kbin.social
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        1 year ago

        You do know anxiety itself carries a heart attack risk, right? A person without anxiety taking propanolol might increase the risk, but for someone with crippling anxiety I’d wager it might be a net benefit.

        • auhu@kbin.social
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          1 year ago

          I was referring to mixing cocaine with propranolol

          edit: I think something broke lol
          It looks like I somehow replied to every reply to the original comment and now I look like a jackass

          oopsie

    • happyspark@kbin.social
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      1 year ago

      Propanolol (and other beta blockers) … blocks a type of` receptor found on cells call beta adrenergic receptors. In the heart, beta blockers work to help with rate control.
      Cocaine activates beta and alpha adrenergic receptors. Activating alpha adrenergic receptors can cause vasoconstriction.

      Combining them, you get unopposed alpha activity, leading to coronary artery constriction, and a significant increase in risk of heart attack.

      edited to change “ion channel” to “receptor