I mean, you’ll find people using PEDs in any sport, despite the risk of bans and everything. Steroid use is also rampant among bodybuilders.
There is an “obvious market”, but why do such sport leagues or federations that openly allow those drugs exist?
I can imagine that such a thing existing would create an immediate and widespread health problem with lots of people, athletes or not, using those performance enhancers and accidentally fucking themselves. But what else could be a problem?
The analogy with esports fails only because real people would still be limited by their own bodies, there’s only so many drugs anyone can take before the body starts failing, not to mention that they don’t make people godlike as some cheats do.
Depending on the speedhack allowed and the game, it could be entertaining to watch, it’d become a game of human reflexes.