I upgraded my PC recently, and did a clean install of windows 10. I’m now using an ASUS TUF Gaming Z690-Plus Wifi D4 motherboard with my old G Skill Trident Z RGB sticks that worked with OpenRGB before upgrading. So the issue is likely the motherboard. I just don’t know why it’s not reading the memory. I tried enabling the SPD Write option in the BIOS, but that didn’t solve it. OpenRGB recognizes everything else that’s plugged in, keyboard, mouse, even the RGB zones built into the motherboard. I don’t have any other programs that would control RGB, and don’t see any services running that would either.
Issue was solved by updating the chipset driver. Didn’t realize I hadn’t installed the chipset driver thanks to ASUS’ support/download pages design.