Silk has been cultivated for centuries by domesticated silkworms, but it has been difficult to commercially produce spider silk in bulk due to their cannibalistic tendencies. However, spider silk fibers are attracting attention for their fineness, mechanical properties, and lustrous appearance. Spider silk produced through recombinant protein expression systems and chemical synthesis has shown to have superior properties for medical use to prevent the formation of blood clots and have excellent knot strength to endure repetitive loading and unloading. In this study, the cell adhesion behavior of native spider silk was investigated.

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