For me (list will be extended):

• Nicotine: pushing, large doses make me shiver, very easy to obtain, easy to become addicted
• Diazepam: very calming, gives a bit of high, easy to sleep, sometimes hangover (a bit unpredictable). High potential for addiction, long half-life, so it stacks in effect which means you can’t take too much on consecutive days. Pretty easy to get.
• Cannabis: lots of different strains, most of them very relaxing, opens the floodgates of your thoughts. Easy to get, nearly no physical addiction, but I know a few stoners who can’t get their life in order because they smoke too much.
• alcohol: very predictable, very easy to get, easy to overdose, hangovers are real once you get older. There are some beverages which taste very good.
• MDMA: very, very uncomfortable for me. Had pretty good mood, but felt like I was full of ants and constantly had to do stuff. Makes you horny aswell. Party drug for people who are already annoying at parties. Easy to get on every rave.
• Propofol: You can get this at the dentist. Knocks you out but doesn’t do much more. You don’t really have time to enjoy it, even in low doses. Wouldn’t make me addicted. Can go horribly wrong.
• Methylphenidate: makes you productive, you feel centered and very alert. Not a lot of fun but if you want to get shit done, pretty reliable and predictable. Medium risk. Your heart can just stop like with other amphetamines.
• Caffeine: the pussy version of MDMA. Many people become addicted and need more and more of this stuff to function. Coffee tastes awful to me.
• Tilidine: happy drowsy pills. Is probably very risky and makes very addicted (see opioid crisis in the USA). Predictable, but you also can’t do much when you took it.